Approaches to Selecting “Time Zero” in External Control Arms with Multiple Potential Entry Points: A Simulation Study of 8 Approaches

As a spinoff from answering a methodological question for a client, the team have led on a paper (now in press) conducting a simulation of how to handle multiple potential start points being available for real world data comparisons. This forms part of a special issue of MDM.

You can read the open access article by following this link: